EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.4 | additional information | dietary supplementation of branched-chain amino acid over several weeks increases the enzyme activity in spontaneous type II diabetic rats, overview | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.4 | additional information | Rattus norvegicus | The branched-chain alpha-keto acid dehydrogenase complex is the most important regulatory enzyme in branched-chain amino acid catabolism, regulation of hepatic BCKDH complex activity in spontaneous type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats and Zucker diabetic fatty rats, both showing reduced enzyme activity, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.4 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.4 | liver | type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats and Zucker diabetic fatty rats | Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.11.4 | additional information | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.4 | additional information | The branched-chain alpha-keto acid dehydrogenase complex is the most important regulatory enzyme in branched-chain amino acid catabolism, regulation of hepatic BCKDH complex activity in spontaneous type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats and Zucker diabetic fatty rats, both showing reduced enzyme activity, overview | Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.4 | BCKDH | - |
Rattus norvegicus |
2.7.11.4 | branched-chain alpha-keto acid dehydrogenase | - |
Rattus norvegicus |